Maxisim 2000 medical equipment pdf manual download. For in vitro diagnostic use with the immulite 2000 analyzer for the quantitative measurement of human growth hormone in serum, as an aid in patient management. Conventions to improve readability, the following conventions are used. The immulite system provides proven reliability year after year. Used siemens immulite 2000 xpi unit immunology for sale. Immulite, immulite, immulite 2000, immulite 2000 xpi. Current reliability of the immulite assay for measurement of. Material safety data sheet for immulite growth hormone hgh. The siemens immulite 2000 xpi immunoassay system may be purchased in 1 of 2 ways listed below. Pediatric reference intervals for fsh, lh, estradiol, t3, free t3, cortisol, and growth hormone on the dpc immulite. Immulite 20002500 front view 1 2 3 6 8 7 liquidw aste 14 12 4 5 10 91115 distilledw ater number component number component 1 sample carousel 9 reaction tube hopper 2 reagent carousel covered 10 liquid waste 3 pipettors 11 probe wash 4 drd priming accessories 12 distilled. Growth hormone gh is so similar structurally to prolactin that. All rights of this immulite 20002500 operators manual file is reserved to who prepared it. Siemens immulite 2000 2500 reagents and consumables we supply original reagents and consumables for siemens immulite 2000 2500.
Immulite 2000 age and sexspecific reference intervals for. Immuliteimmulite growth hormone hgh,immulite and immulite assays are designed for use with the immulite and immulite, continuous random access immunoassay analyzers which offer simplicity in both design and operation. Random measurements of gh are difficult to interpret. The immulite system is a bench top immunoassay analyzer. Immulite 20002500 operators manual free pdf download.
Measuring growth hormone and insulinlike growth factori in infants. Beckmancoulter and three were performed using a manual pro. Pediatric reference intervals for fsh, lh, estradiol, t3. Intraassay precision for the immulite 2000 varied between 4. Impact of the choice of igfi assay and normative dataset on the. Antihbc total antihbs hbsab quantitative hbsag hbsag confirmatory. The immulite 2000 xpi system is a continuous random access immunoassay analyzer with a maximum throughput of 200 tests per hour. Determinants of the growth hormone nadir during oral. Growth hormone deficiency and moyamoya disease 205 cerebrovascular lesions suggestive of moyamoya disease. The new immulite 2000 xpi is a continuous, random access analyzer with a throughput of up to 200 tests per hour.
This design increases workflow and enhances productivity for medium to highvolume immunoassay laboratories by incorporating specialty and. Siemens medical solutions diagnostics gmbh, fernwald, germany. The methods are similar in that they are both used for the quantitative. Enhanced chemiluminescent technology and a proprietary wash technique permit true thirdgeneration performance. Growth hormone clinical criteria information included in this document excluding serostim zorbtive drugs requiring prior authorization. Growth hormone deficiency associated with moyamoya. Standardization of the immulite systems growth hormone assay. Assays were performed according to the manufacturers instructions. Single specified analyte controls assayed and unassayed. Texas prior authorization program clinical criteria drug.
It helps teams move beyond driving fleeting, surfacelevel growth to instead focus on generating longterm retained customer growth. Immulite kits barcoded for scanning all reagent information. Used siemens immulite unit immunology for sale dotmed. This design increases workflow and enhances productivity for medium to highvolume immunoassay laboratories by incorporating specialty and allergy testing into one platform. The immulite 2000 2500 operator s manual describes the operation of the immulite 2000 and immulite 2500 instruments and software. Accessgudid immulite 2000 systems tes total testosterone 00630414962221 testosterone immulite rgt 600 tests. Siemens immulite 20002500 reagents and consumables. The cobas c 501 module is a fully automated, medium throughput module that performs photometric assay tests for a wide range of analytes over 110 clinical chemistry tests available, including proteins, enzymes, substrates, electrolytes, hba1c, and more. Feb 19, 2017 lis interface to immulite 2000 xpi to. Texas prior authorization program clinical criteria drugdrug.
Preanalytical influences on dpc immulite 2000 intact pth assays of plasma and serum from dialysis patients. Pdf the aim of our study was to evaluate the betweenassay variability of commercially available. Human growth hormone hgh conversion to miul, ngml, ng. The highly reliable immulite 2000 xpi system is easy to use and has one. Loaded with articles, videos, podcasts, and more, product manual is your essential guide to building remarkable products. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. View and download bc biomedical maxisim 2000 user manual online. A study performed at a large reference laboratory in the western united states, using the immulite 2000 growth hormone assay, on 59 healthy adult. Growth hormone gh1 is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Pdf preanalytical influences on dpc immulite 2000 intact. Case report a caucasian male was born at 38 weeks of gestation after a caesarean section, with birth weight 4000 g and birth length 57 cm, with no perinatal problems. His linear growth velocity started to decline at the age of 12 years.
Growth hormone gh, somatotropin, hgh, pituitary growth hormone gh is a member of the large family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. Better than ever other 8% assays 19% reliability 29% ease of use 44% ease of use simple to operate. Pdf harmonization of growth hormone measurements with. The immulite 2000 intuitive software, and graphical user interface, offers streamlined information management, from remote test ordering to sophisticated analysis of results.
As a result, siemens diagnostics is updating the user manuals to reflect the name change. The following steps were followed to operate the instrument as described in the immulite 2000 operators manual. Immulites extensive menu allows immunoassay consolidation, offering more than 75 assays. Searchable database of fda 510k applications and descisions.
It seems purposeful to determine the significance of ghst and igfi assessment in diagnosing ghd. Growth hormone antibody gh45 dylight 350 nb500364uv. Utility of serum igf1 for diagnosis of growth hormone deficiency. The immulite 2000 immunoassay system has been designed specifically for optimum efficiency and consolidation in medium and highvolume laboratories. We supply original reagents and consumables for siemens immulite 20002500. Immulite 2000 human growth hormone immulite 2000 pappa immulite 2000 pth intact immulite 2000 rubella igm immulite 2000 rubella quantitative igg. The growth hormone gh secretion is routinely evaluated in children with short stature, on the ground of the results of gh stimulating tests ghst with different pharmacological stimuli 1, 2. Method comparison immulite 2000 i immulite 2000 xpi against immulitei immulite insulin kitlot401piulml 3u 129 2. Determinants of the growth hormone nadir during oral glucose tolerance test in adults. Pharmacokinetics of oral cyanocobalamin formulated with. Earlier, the assay had been reported to overestimate igf1 concentrations. Dpc immulite analyzer was used for the quantitative. National library of medicine nlm tools and resources fda udi home fda medical devices home report a device problem medwatch.
Pdf type ia isolated growth hormone deficiency ighd. Jan, 2011 the diagnosis of growth hormone gh deficiency ghd in short children seems unquestionable when both gh peak in stimulating tests ghst and igfi concentration are decreased. Correspondence should be addressed to p j monaghan email phillip. Insulinlike growth factori igfi is the main peripheral mediator of gh activity. Mod4023 longlasting human growth hormone hgh study. Grow your users is to understand the growth drivers at each stage acquisition, activation, conversion, retention, referral and then. This list suggests that prolactin is an ancient hormone whose functions have diversified during the evolution of the various vertebrate groups. Immulite for your automated immunoassay testing needs. Contribute to levinalexlis development by creating an account on github. Immulite 2000 age and sexspecific reference intervals for alpha fetoprotein, homocysteine, insulin, insulinlike growth factor1, insulinlike growth factor binding protein3, cpeptide, immunoglobulin e and intact parathyroid hormone. This reference guide includes overviews of the systems, configuration instructions, and operating, maintenance, and troubleshooting procedures. This study was conducted to compare the pharmacokinetics and tolerability of 2 oral formulations of cyanocobalamina marketed cyanocobalamin tablet immediaterelease b12 5 mg and cyanocobalamin formulated with a proprietary carrier, sodium n82hydroxybenzoylaminocaprylate snacto establish the feasibility of using an absorption enhancer with b12 to improve uptake of.
Immulite systems can be found in a wide variety of immunoassay testing environments around the world. Bc biomedical maxisim 2000 user manual pdf download. Backgroundthe diagnosis of disorders of growth hormone gh. Fda 510k applications for medical device product code jjx single specified analyte controls assayed and unassayed. Growth hormone was measured by a onestep immunometric chemiluminescent immunoassay using the siemens immulite 2000 xpi platform. Growth hormone deficiency associated with moyamoya disease in. Based on its relationship to immulite 2000 growth hormone see method comparison 1 the assay can be expected to have esentially the same reference ranges.
Immulite immulite against immulite2000 immulite2000xpi insulinmethod compaiison a cross platform comparison ofcorrectedinsulin kitlots, 40i and above, is shown infigure3, whichdemonstrates good cross platform agreement. The siemens dpc immulite may be purchased in 1 of 2 ways listed below. However, the discrepancies between the results of ghst and igfi secretion are observed. Customer input was the basis for this new design that maximizes workflow and. All children with ghd were recruited from paediatric endocrine units please refer to the. Oct 21, 2010 this study aims to assess the safety, tolerability and pharmacokinetics pharmacodynamics pkpd profile of three doses of mod4023 on a weekly regime and one dose on an everyotherweek regime administered for a period of 4 weeks in growth hormone deficient adult ghda patients who previously were on a stable rhgh treatment. Each cobas c 501 module will perform up to 1,000 tests per hour 600 photometrics tests per hour and 400 ise tests per hour. You can add community subscriptions in the search bar that says subscribe to more communities. Patient results using the immulite 2000 were accessed and used to. The north star metric nsm is a powerful concept that has emerged in recent years from silicon valley companies with breakout growth.
The calibration range was from 20 to 2000 pgml and the analytical sensitivity was 15 pgml. Laboratory studies of insulin, 23 heparin, 24 cromolyn, 25 and human growth hormone 26 when coformulated with snac have shown that the carrier aids gastrointestinal absorption by. Threeyear efficacy and safety of lb03002, a onceweekly sustainedrelease growth hormone gh preparation, in prepubertal children with gh deficiency ghd. Online conversion calculator for many types of measurement units in laboratory and medicine human growth hormone hgh, growth hormone, sth, somatotropin. Usa, sample processed according to manufacturers instructions, 63. Siemens dpc immulite 2500 reagents prolactin l5kpr6 mr. We have 2 siemens immulite homocysteine 2000 manuals available for free pdf download. Training provided wpurchaseadvanced operator training. Immulite 2000xpi 3gallergy specific ige apple component allergen, rmal d 1 malus domestica, a464l2 background mal d 1 is a pr10 protein associated with oral allergy syndrome oas to apple. Immulite 20002500 operators manual pdf view and downloadable. Method comparison immulite 2000 i immulite 2000 xpi against immulitei immulite insulin kitlot401piulml. Service and user manual for siemens immulite analyzer.
What do customers say they like most about their immulite. Developed for and tested with dpc immulite i2500 user manual using the lis specification version 600129h not available online, but a similar version might be available. This study aims to assess the safety, tolerability and pharmacokinetics pharmacodynamics pkpd profile of three doses of mod4023 on a weekly regime and one dose on an everyotherweek regime administered for a period of 4 weeks in growth hormone deficient adult ghda patients who previously were on a stable rhgh treatment. Europe pmc is a service of the europe pmc funders group. Siemens dpc immulite 2500 reagents prolactin l5kpr6 use request form below ordering immulite reagents. Unit conversion tables, 2nd edition, endocrine sciences, 4301 lost hills rd, calabasas hills, ca 91 biorad lyphochek immunoassay plus control product insert. Growth hormone gh 22kda immulite 2000 dynamic stimulatory or inhibitory tests are used for the diagnosis of gh deficiency or excess. Additionally, gh is a 191amino acid, singlechain polypeptide that is. It is recommended that no more than 32 wells be used for each assay run. Immulite 2000 age and sexspecific reference intervals for alpha. The immulite 20002500 operators manual describes the operation of the immulite 2000 and immulite 2500 instruments and software. Immulite immulite growth hormone hgh, immulite and immulite assays are designed for use with the immulite and immulite, continuous random access immunoassay analyzers which offer simplicity in both design and operation. The immulite assay, the test most commonly used for igf1 measurement by clinical laboratories in brazil, recently had supply problems and temporarily ceased to be used. Immulite 2000 growth hormone hgh 2 immulite 2000 growth hormone hgh pil2kgh14, 20050509 english intended use.
Thyroid hormone is important for a normal response to agents that stimulate gh secretion. Immuliteimmulite growth hormone hgh 2 immuliteimmulite growth hormone hgh pilkgh12, 20050509 english intended use. Genes for growth hormone gh are found in a gene cluster on 17q, which consists of two growth hormone genes and three csh genes. Siemens immulite homocysteine 2000 manuals manuals and user guides for siemens immulite homocysteine 2000. Immulite2000 tsi assay immulite2000 tsi calibration verification material cvm indications for use describe the immulite 2000 tsi thyroidstimulating immunoglobulins assay is an in vitro diagnostic immunoassay for the semiquantitative determination of thyroid stimulating autoantibodies specific to thyroid stimulating hormone receptors. Feb 06, 2015 12 6008490001a immulite 2000 2500 operator s manual figure 3. Do igfi concentrations better reflect growth hormone gh. The antibody gh45 reacts with human growth hormone hgh, a polypeptide hormone synthesized by acidophilic or somatotropic cells of the anterior pituitary gland.
Insulinlike growth factor igrowth hormone deficiency in. The role of growth hormone gh and insulinlike growth factori igfi. Mod4023 longlasting human growth hormone hgh study in. For in vitro diagnostic use with the immulite and immulite analyzers for the quantitative measurement of human growth hormone hgh in serum, as an aid in patient management. The methods are similar in that they are both used for the quantitative determination of tsh in serum, and both use tsh calibrated and labeled in iuml standardized to the who htsh 2nd irp, 80558. Type ia isolated growth hormone deficiency ighd consistent with compound heterozygous deletions of 6. An extensive menu, ease of use, robust hardware and excellent assay performance makes this system a great choice for the small.